Dallas,TX (PRWEB) August 31, 2012

Septembeard is an organization with a simple, focused goal: eradicating prostate cancer, the second leading cause of cancer deaths in men according to http://www.septembeard.org. There are three basic ways to be a part of Septembeard; growing solo, creating a team or simply making contributions. The first step is to visit the website and create a profile. For men, this is when the growing begins. The next step is to spread the word and collect donations. Get creative and make a contest out of it. Be a hero and sleep in longer in the mornings. What is better than that? For more information or to learn how to participate please visit http://septembeard.org/

Both Equinox and The Gents Place are teaming up together to encourage clients to sign up and participate. On Sunday September 30th, an event will be held at The Gents Place Preston Hollow club from 5:00-7:00 pm celebrating all that the participants have accomplished during the month.

Whether the man wants to trim it up or take it off… The Gents Place is hosting an event to do just that. They are offering participating men complimentary straight razor shaves or beard trims. But that’s not all; the event will also have the House of Cigars on site hand rolling organic cigars for purchase as well as complimentary beverages.

The Gents Place and Equinox would like to send out a special invite to anyone and everyone who would like to be a part of the event. Please RSVP to Jennifer Berry at jberry (at) thegentsplace (dot) com by September 21st.

About The Gents Place

Founded in 2008 by Ben Davis, a frustrated guy who hated getting his haircut, The Gents Place offers men’s grooming and lifestyle products and services in a masculine, yet relaxed country club type environment. They offer men’s hair services, hand and foot repairs, straight razor shaves, massages, shoe shines and more. Frequently referred to as America’s Premier Men’s Grooming and Lifestyle Club with locations in Texas (Dallas, Frisco) and Kansas (Leawood), The Gents Place is known for its commitment to client service and top shelf amenities. For more information about The Gents Place or to find a club near you please visit http://www.thegentsplace.com/

 About Equinox

For twenty years, Equinox Fitness Clubs has provided an unparalleled member experience, setting new standards from personal training to group fitness to rejuvenating wellness treatments. Located in the active, social community of North Dallas, the Preston Hollow club features include a boxing studio, dedicated yoga and cycling studios, and a developmentally-focused Kids Club just to name a few. To find a club closest to you or to learn more about Equinox, please visit http://www.equinox.com/

Their findings may eventually be used to predict which cancers are likely to return

In a study to decipher clues about how prostate cancer cells grow and become more aggressive, Johns Hopkins urologists have found that reduction of a specific protein is correlated with the aggressiveness of prostate cancer, acting as a red flag to indicate an increased risk of cancer recurrence. Their findings are reported online in the Proceedings of the National Academy of Sciences on Aug. 27, 2012.

The team focused on a gene called SPARCL1, which appears to be critically important for cell migration during prostate development in the embryo and apparently becomes active again during cancer progression.  Normally, both benign and malignant prostate cancer cells express high levels of SPARCL1, and reduce these levels when they want to migrate. The team correlated this reduction or “down regulation” of SPARCL1 with aggressiveness of prostate cancer.

“Our findings should allow physicians to not only pinpoint those patients whose cancers are destined to return after surgery, but could also reveal a potential new option for treatment,” says Edward Schaeffer, M.D., Ph.D., an associate professor of urology, oncology and pathology at the Johns Hopkins University School of Medicine and co-director of the Johns Hopkins Prostate Cancer Multidisciplinary Clinic.

In their study, Schaeffer and lead investigator Paula Hurley, Ph.D.,  also found that SPARCL1 seems to play a role in predicting tumor recurrence in a number of other diseases including bladder, breast, colon, rectum, tongue, lung, skin and ovarian cancers.

The team is now working to decipher the specific mechanism that controls the gene in hopes of developing a treatment that can reset SPARCL1 to normal levels and potentially prevent a patient’s cancer from recurring. Hurley is currently investigating novel genes that are not only prognostic of lethal prostate cancer but also contribute to prostate cancer progression to metastasis.

According to the American Cancer Society, about 240,000 men in the United States are expected to be diagnosed with prostate cancer this year; the majority are over age 65.  The disease is the second leading cause of death among U.S. men. An estimated 28,000 men in the U.S. will die of prostate cancer this year.

“While many of our patients are initially cured with surgery, some inexplicably have their cancers return,” says Schaeffer. “We are working to identify patients at higher risk of recurrence and our ultimate goal is to develop new treatments that would prevent the return of the cancer.”

 Funding for the study was provided by the U.S. Department of Defense Prostate Cancer Research Program.  Corresponding grant numbers are DOD-W81XWH-10-2-0056 and W81XWH-10-2-0046 PCRP Prostate Cancer Biorepository Network (PCBN).  Additional support was provided by the Flight Attendant Medical Research Institute YSCA, the Patrick C. Walsh Prostate Cancer Fund at Johns Hopkins, the Howard Hughes Medical Institute Early Careers Physician Scientist Award, the American Urological Association Astellas Research Star Award, and the National Institute of Health, with corresponding grant number P3-0CA006973.

In addition to Schaeffer and lead investigator Hurley, other Johns Hopkins researchers involved in this study were Luigi Marchionni, M.D.; Brian Simons, D.V.M.; Ashley Ross, M.D., Ph.D.; Sarah Peskoe, Sc.M.; Rebecca Miller, B.S.; Zhenhua Huang, Ph.D.; Bora Gurel, M.D.; Ben Park, M.D., Ph.D.; and Elizabeth Platz, Sc.D., M.P.H.  Other investigators included Nicholas Erho, M.Sc.; Ismael Vergera, Ph.D.; Mercedeh Ghadessi, M.Sc.; and Elai Davicioni, Ph.D., at GenomeDx Biosciences Inc., in Vancouver, Canada; as well as Robert Jenkins, M.D., Ph.D., at the Mayo Clinic in Rochester, Minn.; and David Berman, M.D., at Queens University in Kingston, Canada.  

Johns Hopkins Medicine

Media Relations and Public Affairs

Media Contact:  Ellen Beth Levitt, eblevitt@jhmi.edi

410-955-5307

Just print out these posters and flyers, and post them somewhere that your friends and co-workers will see them. Give everyone a chance to grow, and help make 2012 Septembeard’s best year yet!

Flyer (8.5 x 11”)
Download PDF (1.9 MB)

Poster (11” x 17”)
Download PDF (2.9 MB)